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Outcomes of the study indicate that dosage kind performance can be considerably completely different in particular person subjects and spotlight the significance of addressing particular person physiological parameters related to intraluminal drug release when the purpose is to foretell the in vivo performance of locally-performing mesalazine formulations in particular person patients.
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Compared with non-teratogens, mesalamine led to a lower beginning weight and an increase in the preterm supply fee; the effect for birth weight was higher in women whose inflammatory bowel disease was lively during pregnancy and in those who received mixture remedy.